Formulasi Dan Evaluasi Fisik Sediaan Suspensi Kombinasi Ekstrak Biji Pepaya (Carica Papaya L.) Dan Umbi Rumput Teki (Cyperus Rotundus L.) Dengan Variasi Konsentrasi Suspending Agent Pga (Pulvis Gummi Arabici) Dan Cmc-Na (Carboxymethylcellulosum Natrium)

نویسندگان

چکیده

Suspension preparations are made because some of the active substances have a solubility that is practically insoluble in water, but required liquid form. Among medicinal plants water papaya seeds (Carica L.) and teki grass tubers (Cyperus rotundus L.), so they form suspension to produce stable preparations. Papaya pharmacological activities as antibacterial, laxative pancreatic lipase inhibitors. In formulation extracts tubers, combination suspending agents PGA (pulvis gummi arabici) CMC-Na (Carboxymethylcellulosum Sodium) was used. at concentration less than 10% has low viscosity it can accelerate sedimentation, combined with which agent increase stability. The purpose study determine effect on physical properties nut what could provide best quality among four formulas made. Evaluation stability carried out for 4 weeks after preparation included organoleptic, homogeneity, pH, density, viscosity, sedimentation volume redispersion. From research results, known carboxymethylcellulose affect

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ژورنال

عنوان ژورنال: Cendekia Journal of Pharmacy

سال: 2021

ISSN: ['2599-2155', '2599-2163']

DOI: https://doi.org/10.31596/cjp.v5i2.160